Failed to access IIS metabase

if you try to run .aspx file in IIS server and got error like "Failed to access IIS metabase"

The easy solution for this error is:
Open visual studio command prompt and type this command
aspnet_regiis -ga \username
                   Here username is usually aspnet
if this doesn't work than use this command
aspnet_regiis -i

alternatively you can copy and paste this command into windows command prompt

%windir%\Microsoft.NET\Framework\v2.0.50727\aspnet_regiis.exe -i

this will fix your problem